Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. As opposed to opioids, which bind to µ-opioid receptors from the central anxious technique, conolidine modulates alternate molecular targets. A Science Developments review identified that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabil... https://conolidine55296.webbuzzfeed.com/38119706/what-does-alternative-natural-pain-relief-to-replace-traditional-painkillers-mean