You will find there's release of norepinephrine from your descending inhibitory bulbospinal neurons that binds to alpha-two-receptors during the dorsal horn to decrease afferent suffering transmission and make analgesia. Consequently, medication like clonidine that target alpha-two receptors can influence the transmission of agony. This document doesn't have all possible https://everettv738lcr3.dekaronwiki.com/user