There exists a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors during the dorsal horn to reduce afferent suffering transmission and develop analgesia. Thus, medications like clonidine that goal alpha-2 receptors can affect the transmission of soreness. One of several theories concerning the mechanism https://josefam036pnj8.wikiexpression.com/user