Deep, focused future-generation sequencing has unveiled that subclonal mutations (i.e., those current in just a portion of tumor cells) may be detected for all driver genes and so are related to quick disorder progression and inadequate final result.eleven–thirteen This is especially related for TP53 The clinical system of CLL is https://linkalternatifmbl7765433.dreamyblogs.com/33407498/detailed-notes-on-mbl77