Minor (1)carbamazepine will decrease the level or effect of caffeine by impacting hepatic enzyme CYP1A2 metabolism. deferasirox will decrease the extent or impact of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Use ergot alkaloids with warning with considerably less powerful CYP3A4 inhibitors. caffeine improves toxicity of bupropion by https://johnnyjfytk.bloggazza.com/27221924/facts-about-cafergot-discontinued-revealed